Form of Antibody:NS-20284-H-Bromo-1,2,4-oxadiazolo[3,4-d]benz(b)oxazin-1-one
Purity:98% by TLC
Solubility:Soluble in DMSO
Storage/Stability:Store solutions at -20°C for up to 1 year.
Recommended Dilutions:Potent, selective, cell permeable, irreversible inhibitor of soluble guanylyl cyclase. Inhibition of GNSO induced soluble GC activity in mouse cerebellum homogenate, IC50=17 nM. Complete inhibition of NO induced relaxation in vascular and nonvascular smooth muscle at 1 μM.
References:S.P. Olesen et al. Br. J. Pharmacol. 1998 123 299